Amy Sedaris is one of the funniest comedic performers of all time. I was going to say funniest female comedic performers, but I realized that’s just stupid. Her talent shouldn’t be subjugated to some gender consignment. She’s a performance genius, and if you’ve never seen “Strangers With Candy,” the mastermind show created by Amy, Paul Dinello, and Steven Colbert, do yourself a favor and track it down right now. I’m pretty sure every episode is available for free on comedycentral.com. Anyway, Amy does most of her performing these days on the Letterman show, as she became one of Letterman’s most frequent and favorite guests. When she does Dave’s show, she is like a rocket of spirit, laughs, and quirky charm. Every time she is on, she makes Dave and the audience fall head over heals in love with her. What I have below is Amy’s most recent appearance on the Late Show, and she talks about turning 50, touching the elderly, root canals, and Keith Richards. It’s really a joyful interview, and if you like it, there are no shortages of her appearances on youtube, and they’re all great. Enjoy.